Monday, April 6, 2015

Why metformin and PCOS?

Some have been asking why metformin so here is a little tidbit that may help clarify: Young women with PCOS often have elevated insulin levels and are more likely to develop diabetes. What is insulin? Insulin is a hormone made by an organ in the body called the pancreas. The food you eat is broken down into simple sugar (glucose) during digestion. Glucose is absorbed into the blood after you eat. Insulin helps glucose enter the cells of the body to be used as energy. If there’s not enough insulin in the body, or if the body can’t use the insulin, sugar levels in the blood become higher. What is insulin resistance? If your body is resistant to insulin, it means you need high levels of insulin to keep your blood sugar normal. Certain medical conditions such as being overweight or having PCOS can cause insulin resistance. Insulin resistance tends to run in families. What can insulin resistance do to me? In young women with PCOS, high insulin levels can cause the ovaries to make more androgen hormones such as testosterone. This can cause increased body hair, acne, and irregular or few periods. Having insulin resistance can increase your risk of developing diabetes. Metformin helps to regulate the amount of glucose (sugar) in your blood. It makes your body more sensitive to insulin, and decreases the amount of glucose your liver releases. Research studies have shown that young women with PCOS who are overweight and who were treated with Metformin and a healthy lifestyle (healthy nutrition and exercise) were able to lose weight and lower their fasting blood sugar. Metformin is not approved by the FDA (Federal Drug Administration) for PCOS, but it’s commonly prescribed for this condition.

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